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EU4Health 2025 calls for proposals: advancing crisis preparedness through diagnostics and medical countermeasures

On 4 September, HERA published two new calls for proposals under EU4Health to strengthen Europe’s preparedness against health crises. These calls aim to accelerate the development of innovative diagnostic tools for vector-borne diseases and support the advancement of medical countermeasures.

Diagnostics for vector-borne diseases

The call for proposals EU4H-2025-HERA-PJ-2 seeks to strengthen preparedness against mosquito-borne diseases by supporting the late-stage development of rapid and sensitive diagnostic tests.

Vector-borne diseases such as dengue, Zika, chikungunya, and West Nile virus are an increasing challenge for public health in the EU. Current diagnostic tools often lack sufficient sensitivity and specificity, suffer from cross-reactivity, and have limited ability to test for several conditions at the same time. These shortcomings contribute to underdiagnosis and delayed treatment.

The new action will support the development of innovative and cost-effective diagnostic solutions that:

  • Enable timely detection and diagnosis in resource-limited settings.
  • Reduce reliance on central laboratory infrastructure.
  • Improve early treatment and help limit transmission.

Indicative budget: EUR 10 million, with 2–3 grants expected.
Project duration: 36–48 months.
Target applicants: Higher education institutions, research organisations, hospitals, healthcare institutions, NGOs, diagnostic developers, and other public or private entities with relevant expertise.

Medical countermeasures for CBRN threats

The second call for proposal supports the development of innovative medical countermeasures for CBRN threats, structured around three topics:

  • EU4H-2025-HERA-PJ-1-a: Medicinal products (vaccines and treatments, focusing on threat-agnostic and platform-based approaches, especially for biotoxins).
  • EU4H-2025-HERA-PJ-1-b: Reusable respiratory personal protective equipment (PPE) and protective suits.
  • EU4H-2025-HERA-PJ-1-c: Innovative detection and diagnostic tools for chemical and biological threats.

CBRN incidents may be of low probability but potentially high impact. Advances in biotechnology and today’s geopolitical context underscore the importance of strengthening Europe’s preparedness. Activities funded under these topics are expected to bridge the gap between research, innovation, market access, and deployment.

Indicative budget: EUR 20 million across the three subtopics.
Project duration: 24–48 months, depending on the subtopic.
Target applicants: Higher education institutions, research organisations, hospitals, expert networks, security practitioners, end users, and other public or private entities.

Application details

Interested parties are invited to submit proposals via the EU Funding and Tenders Portal by 4 December 2025, 17:00 CET. Recordings and presentations from the dedicated webinars, organised by HERA and HaDEA, are available on the EU Health Policy Platform (password: @HPP_webinar2025).